In a study which was done by Mysorekar et al., of the 145 lesions which were examined, 102(70.3%) were nonneoplastic and 43(29.7%) were neoplastic 21(48.8%) were benign and 22 (51.2%) were malignant. Among 129 benign neoplasms, they found that a majority were hemangiomas which were seen in 59(45.7%) cases and among the 41 malignant neoplasms, 15(36.6%) were squamous cell carcinomas. In their study, among the nonneoplastic lesions, true nasal polyps accounted for 110(63.8%) cases 74(63.3%) being allergic and 36(32.7%) being inflammatory ones. In a similar study which was carried out on 345 cases, Dasgupta et al., found 175 (50.7%) non neoplastic lesions and 170 (49.3%) neoplastic lesions. One interesting case of a sinonasal adenocarcinoma was seen in a 60 years old male. This was followed by three cases of non-Hodgkin's lymphoma in elderly patients (50-60 years). Sinonasal undifferentiated carcinomas were predominantly seen in the age group of 40-50 years. A majority were sinonasal undifferentiated carcinomas 41% (7/17), followed by squamous cell carcinomas 35% (6/17). Malignant tumours were seen in 50% (17/34) of the neoplastic cases. The other important benign tumours were one case each of a capillary haemangioma and a microcystic papillary adenoma. Next in frequency were three cases of schwannomas these cases were seen in elderly females who were aged 54, 50 and 62 years. Inverted papilloma was also predominantly seen in men (4/6) who were in the age group of 30-70 years. Angiofibromas were seen in the younger age group (11-40 years). Angiofibroma and inverted papilloma were the most common benign tumours. Seventeen cases each of benign and malignant tumours were seen. On taking all the cases of nonneoplastic lesions together, it was seen that there were 46 males against 20 females and the average age was 39 years (7-71 years). These were common in younger patients (22/35), who were in the age range of 11-45 years. There were 23 males and 12 females with inflammatory nasal polyps and 6 males and 3 females with allergic nasal polyps. The allergic nasal polyps have eosinophils infiltrating the stroma, whereas the inflammatory polyps have an oedematous fibrous stroma with a pseudocyst formation and infiltration with lymphocytes and plasma cells. The true nasal polyps were further subdivided into allergic nasal polyps and inflammatory polyps. Two cases of rhinosporidiosis and one each of an inflammatory pseudotumour, fibrous dysplasia, chronic hypertrophic rhinitis and rhinoscleroma were seen. True nasal polyps (44) were the commonest non neoplastic lesions which were encountered in this study, followed by four cases of granulomatous inflammations and mucormycosis each. Nonneoplastic and benign tumours were common in younger age groups whereas malignant tumours were most common in older males.Ĭonclusion: The majority of polypoidal lesions in the nasal cavity are nonneoplastic. The most common malignant tumour was anaplastic carcinoma 7/17(0.4%). Angiofibroma and inverted papilloma were the most frequent benign tumour accounting for 12/17(0.7%). True nasal polyps both inflammatory and allergic together comprised 44 cases of the 100 polypoidal lesions in the nasal cavity. Results: Analysis of 100 polypoidal lesions in the nose and paranasal sinuses with clinical diagnosis of nasal polyps, revealed 66 cases were nonneoplastic and 34 were neoplastic 17 (50%)were benign and 17(50%) were malignant. The neoplastic lesions were further classified according to WHO classification on histopathologic examination. The cases were classified into neoplastic and nonneoplastic lesions. Special stains like Periodic acid Schiff (PAS) was done wherever applicable. The tissues were routinely processed for histopathologic sections and stained with haematoxylin and eosin stains. The age and sex of the patients were recorded. Materials and Methods: The study comprised of 100 consecutive cases of polypoidal lesions in the nasal cavity, received in the department of pathology. They are freely movable and nontender.Īims and Objectives: The purpose of this study was to study the histopathologic spectrum of polypoidal lesions of the nasal cavity. They are overgrowths of the mucosa that frequently accompany allergic rhinitis. Introduction: Nasal polyps are polypoidal masses arising from mucous membranes of nose and paranasal sinuses.
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